Diagnosis and Treatment Skin Diseases - Lupus is a chronic systemic rheumatic disease, which, in addition to affecting the joints and muscles, can damage the skin and almost all organs. Autoimmune basis as that generated by the formation of antibodies. The evolution of the disease develops gradually from the plague and others in which the effects of the disease refers. Also, there are very severe lupus and some not so serious as that which occurs with the skin condition. This disease mainly affects women and the fertile life span (20 to 40 years). They have also been reported cases in children and the elderly.
The cause is unknown. However, be an autoimmune disease there are different factors that can affect the immune system and cause lupus. Several hypotheses have been considered, including genetics and environment. Exposure to the sun can also be a liberating factor pathology. In fact, many people with lupus have photosensitivity to UV. Also, hormones, especially estrogen in women, may be the cause of the disease. In fact, it was observed that the contraceptive pill can accelerate the occurrence in women genetically predisposed.
It is also common hair loss when the disease is active. On the other hand, suffer from lupus patients hypersensitive to ultraviolet light. If the disease is not protected exposed can be reactivated.
When it affects the heart and lungs: layer lining of the heart (pericardium) and the lungs (pleura) become inflamed due to illness. This causes pericarditis and pleurisy. Both have the same symptoms: chest pain and fever. At other times, lupus affects the lungs or heart valve that causes cardiorespiratory failure.
When it affects the kidneys: Lupus always affects both kidneys at a time. The most common injury is inflammation (nephritis), which sometimes prevents the kidneys remove waste from the body enough and it accumulates in the blood. Because of this inflammation, often the kidneys can not absorb and retain protein. With what is excreted in the urine and swelling face and feet occur.
When it affects the brain: Lupus can affect the nervous system. Although generally not important, is the issue that should be monitored. Presenting with headaches, depression or hyperactivity situation. They are very common manifestation in the general population and may be due to inflammation of the brain light lupus or many other circumstances. It is also possible that depression is triggered by the disease, but because of depressed patients know that face this disease, of unknown origin and that can affect many organs of the body.
TYPES OF LUPUS
-Lupus Erythematosus, discoid: chronic, relapsing disease characterized by well defined in the skin of red spots along the edges.
-Lupus Erythematosus: an autoimmune disease with episodes of inflammation in joints, tendons and other connective tissues and organs.
DIAGNOSTICS
The diagnosis is mainly based on symptoms. A blood test can detect antinuclear antibodies present in most individuals with lupus. However, this antibody is also manifested in other diseases, so if antinuclear antibodies are detected, the test should also be done to look for anti-dsDNA antibodies. The high value of the antibody is specific for lupus, but not all people with this disease have antibodies.
Kidney damage caused by lupus can be detected by a blood test and urine, but sometimes kidney biopsy is indicated to further determine treatment.
TREATMENT
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Treatment of this disease is very different depending on the body they affect. Corticosteroids are considered the basic treatment for all affected at one time or another to bring them. If the damaged organs are the lungs, heart, central nervous system or kidneys should be more aggressive treatment and is based on very high doses of corticosteroids and immunosuppressive therapy. If the disease has symptoms such as fever conditions, fatigue or skin, the treatment will be less aggressive and with corticosteroids or antimalarials. Power must be complete, healthy and balanced. No food is harmful to the patient. On the other hand, when the disease affects the kidneys and especially when arterial hypertension patients need to know that it is not advisable to consume salty or spicy foods.
OTHER INFORMATION
A few years ago the pregnancy is contraindicated in women with the disease. However, in recent years the treatment has increased and lower risk. The only formal contraindication for pregnancy is currently active lupus, if there are complications of the disease (nephritis) or if you are taking drugs potentially harmful to the fetus. In addition, pregnant women with lupus have an increased risk of abortion or premature birth. Children are often born healthy. However, in the first few months.
CAUSE
The cause is unknown. However, be an autoimmune disease there are different factors that can affect the immune system and cause lupus. Several hypotheses have been considered, including genetics and environment. Exposure to the sun can also be a liberating factor pathology. In fact, many people with lupus have photosensitivity to UV. Also, hormones, especially estrogen in women, may be the cause of the disease. In fact, it was observed that the contraceptive pill can accelerate the occurrence in women genetically predisposed.
Symptoms of Lupus
Become a multisystem disease that affects multiple organs. Presenting symptoms of common side: Easy fatigue, weight loss can not be explained, not because of prolonged fever and infection process temperature changes. In addition, symptoms of joints and muscles: They are one of the most common clinical manifestations. 90 percent of lupus patients have pain and swelling in the joints (arthritis) in the hands, wrists, elbows, knees and feet more often. You also can appear stiffness in the morning. Also a common skin condition. , If not the most common, known lesion called "erythema butterfly", which consists of redness and rash on the cheeks and nose.It is also common hair loss when the disease is active. On the other hand, suffer from lupus patients hypersensitive to ultraviolet light. If the disease is not protected exposed can be reactivated.
When it affects the heart and lungs: layer lining of the heart (pericardium) and the lungs (pleura) become inflamed due to illness. This causes pericarditis and pleurisy. Both have the same symptoms: chest pain and fever. At other times, lupus affects the lungs or heart valve that causes cardiorespiratory failure.
When it affects the kidneys: Lupus always affects both kidneys at a time. The most common injury is inflammation (nephritis), which sometimes prevents the kidneys remove waste from the body enough and it accumulates in the blood. Because of this inflammation, often the kidneys can not absorb and retain protein. With what is excreted in the urine and swelling face and feet occur.
When it affects the brain: Lupus can affect the nervous system. Although generally not important, is the issue that should be monitored. Presenting with headaches, depression or hyperactivity situation. They are very common manifestation in the general population and may be due to inflammation of the brain light lupus or many other circumstances. It is also possible that depression is triggered by the disease, but because of depressed patients know that face this disease, of unknown origin and that can affect many organs of the body.
TYPES OF LUPUS
-Lupus Erythematosus, discoid: chronic, relapsing disease characterized by well defined in the skin of red spots along the edges.
-Lupus Erythematosus: an autoimmune disease with episodes of inflammation in joints, tendons and other connective tissues and organs.
DIAGNOSTICS
The diagnosis is mainly based on symptoms. A blood test can detect antinuclear antibodies present in most individuals with lupus. However, this antibody is also manifested in other diseases, so if antinuclear antibodies are detected, the test should also be done to look for anti-dsDNA antibodies. The high value of the antibody is specific for lupus, but not all people with this disease have antibodies.
Kidney damage caused by lupus can be detected by a blood test and urine, but sometimes kidney biopsy is indicated to further determine treatment.
TREATMENT
Treatment of this disease is very different depending on the body they affect. Corticosteroids are considered the basic treatment for all affected at one time or another to bring them. If the damaged organs are the lungs, heart, central nervous system or kidneys should be more aggressive treatment and is based on very high doses of corticosteroids and immunosuppressive therapy. If the disease has symptoms such as fever conditions, fatigue or skin, the treatment will be less aggressive and with corticosteroids or antimalarials. Power must be complete, healthy and balanced. No food is harmful to the patient. On the other hand, when the disease affects the kidneys and especially when arterial hypertension patients need to know that it is not advisable to consume salty or spicy foods.
OTHER INFORMATION
A few years ago the pregnancy is contraindicated in women with the disease. However, in recent years the treatment has increased and lower risk. The only formal contraindication for pregnancy is currently active lupus, if there are complications of the disease (nephritis) or if you are taking drugs potentially harmful to the fetus. In addition, pregnant women with lupus have an increased risk of abortion or premature birth. Children are often born healthy. However, in the first few months.
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