Mesothelioma Types
In histological terms, there are four different types of mesothelioma:. Sarcomatoid, epithelial, biphasic and desmoplastic (a variant of sarcomatoid) In medical terms, the term refers to the microscopic examination of cellular tissue histopathology to get an overview of the various manifestations of sarcomatoid mesothelioma diseases.Malignant is the least common of the four cell types. It is responsible for approximately 7-20 percent of cases. When viewed under a microscope, malignant cells appear as elongated spindle cells are irregularly shaped and often overlap one another.Desmoplastic mesothelioma is considered a variant of sarcomatoid mesothelioma. This form is probably the most difficult of all to diagnose mesothelioma. When desmoplastic mesothelioma invade or metastasize, cells may appear very dull and can be confused with benign fibrous tissue.
Medical experts say that this form can not be diagnosed with a core needle biopsy. It is important to know that sarcomatoid malignant mesothelioma is often difficult to diagnose on the basis of histological methods. For example, cells of another type of cancer called sarcomatoid carcinoma lung are very similar in appearance (and other features) for Malignant mesothelioma.For sarcomatoid this reason, if you are diagnosed with cancer and you know you have been exposed to asbestos at some time in the past, obtaining a second opinion diagnosis can be important. Different types of cancer vary widely in terms of prognosis and treatment options, and if misdiagnosed, patients may not receive the most appropriate treatment for cancer.Treatment and PrognosisEach of the four cellular forms of mesothelioma usually is the Likewise. The treatment is not based on the specific type of cells involved, but instead of the location of tumors and cancer stage. Each type of cancer responds to treatment quite differently. In general, patients with sarcomatoid malignant mesothelioma have a worse prognosis than patients with epithelioid type, and sarcomatoid cancer are more aggressive and more resistant to treatment. Unfortunately, the overall prognosis for all different kinds is often poor, and the difference in prognosis between sarcomatoid cancer, epithelioid, biphasic and desmoplastic may amount to only a few months.
Biopsy and Histopathology Patients undergoing medical evaluation to determine the mesothelioma diagnosis will also have to undergo a series of medical tests to determine the location and nature of the cancer.-biopsy: This involves removing samples suspected cancer cells in various parts of the tumor area, which took the laboratory for a proper assessment to determine what type of cells they are and if the cells are malignant.The biopsy samples are tested in the laboratory under the principles of histopathology in two ways: -They are viewed under a microscope to determine their General appearance.-cells evidence of the presence of oncoproteins and molecules that are specific to certain types of cancer cells.When viewed under a microscope, the cells of mesothelioma and other types of cancer cells have different aspect will also be made different forms and compared to normal healthy cells.
More trials evaluating the types of proteins on the surface of cells to determine the exact nature of mesothelial cells become malignant cells.When needed, begin to produce different types of proteins and some of them are present on the surface of the cells. Consideration of the types of proteins on the surface allows to determine whether histólogo are malignant mesothelioma cells, other cancer, or healthy cells. Histochemical application in the diagnosis of mesothelioma are mainly mesotheliomas differentiating epithelial mucin-producing adenocarcinoma
By :. Bello kamorudeen
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